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29th May 2008

Pregnancy stress 'almost doubles risk of stillbirth'

Stressed mothers-to-be are at almost double the risk of stillbirth, research shows.

A study of almost 20,000 women revealed that those who were stressed, anxious or lacked self-esteem in the last weeks of their pregnancy were more likely to suffer a stillbirth.

It is thought that rising levels of hormones in the mother result in the developing baby being deprived of oxygen.

Around 3,500 babies are stillborn in the UK each year - one in every 200.

Researcher Kirsten Wisborg told New Scientist magazine: 'Thankfully, stillbirth is a rare event.

'But we still do not know what causes it and any clues we find can help us reduce the risks.'

Dr Wisborg, of the Aarhus University Hospital in Denmark, made the link between stress and stillbirth after tracking the health of more than 19,000 women during the last three months of pregnancy.

Levels of stress were measured by questioning the women on whether they felt unable to concentrate or handle problems, had lost self-confidence or felt unhappy or unworthy, compared with how they felt just a few weeks earlier.

A third of the women scored highly for stress.

Monitoring of their pregnancies showed that 0.5 per cent of those in the high-stress group suffered a stillbirth, compared with around 0.3 per cent of the less stressed women.

Importantly, the results held up even when high blood pressure, premature delivery and other health problems associated with stillbirth were taken into account.

The researchers said that although the figures were small, the results were significant.

Animal studies suggest the increased risk may be due to raised levels of stress hormones cutting the blood flow to the placenta - and the oxygen supply to the foetus.

Although the effect is likely to be small, if the baby has any other problems, stress could 'tip the balance', said Andrew Shennan, an obstetrician at St Thomas's Hospital in London and spokesman for the baby charity Tommy's.

The next step, he said, is to reduce stress in pregnant women and see if that reduces the number of stillbirths.

Professor Vivette Glover, an expert in stress in pregnancy from Imperial College London, believes there is no time to be lost.

She said: 'People looking after pregnant women should pay much more attention to their emotional health and employers should be open to flexible working hours.'

Professor Glover's work has shown that stress during pregnancy may stunt a child's intelligence.

Children from stressed pregnancies are also more likely to be hyperactive, have emotional problems and not do as they are told as well as suffering from stress themselves.

Stress also trebles the risk of miscarriage in the first weeks of pregnancy.

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