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Understanding pregnancy tests

The most common tests offered are:

Test

Method

Screening or diagnostic

When it can be
done

Ultrasound Scan Screeningand diagnostic From about 8 weeks
Nuchal
translucency test
Scan Screening Around 10-13
weeks
Chorionic villus
sampling
Analysis of placental tissue Diagnostic Around 11 weeks
Amniocentisis Sample of amniotic fluid is tested Diagnostic 13-18 weeks
Alpha feto protein
Double
Triple
Quadruple
Blood tests Screening 16-18 weeks

Before you can make any decisions about which antenatal tests to have (or whether to have any at all), the first thing to understand is the difference between a screening test and a diagnostic test.

Screening test - tells you what your risk is of having a baby with a particular health problem.

Diagnostic test - tells you whether your baby has or has not got a particular health problem.

Screening tests

A screening test estimates your risk of having a baby with a serious health problem such as Down’s syndrome or spina bifida or some rarer condition such as Edward’s syndrome. It can’t tell you for certain whether your baby has or has not got one of these conditions.

So, for example, you might have a blood test when you are 16 weeks pregnant and be told that your risk of Down’s syndrome is 1 in 140. This means that there is only one chance in 140 that your baby will have Down’s syndrome. Or, to look at it another way, you are far more likely to have a normal, healthy baby than a baby with a severe disability.

Name of screening test

When you can have the test

Nuchal translucency test 10 - 13 weeks of pregnancy
Ultrasound scan
(although this
may be diagnostic in some cases)
Any time from 8 weeks of pregnancy
Blood tests 16-18 weeks of pregnancy

 

Screen negative

The result of your screening test may simply be described as screen negative. This means that your risk of having a baby with a problem is less than 1 in 250. Your risk is so small that it’s not even quantified. Nonetheless, a screen negative result does not mean that you definitely have a healthy baby.

Screen positive

If your test result is screen positive (ie, greater than 1 in 250) you will be quoted a figure such as 1 in 100 or 1 in 40. Only you can decide whether you are prepared to accept that risk or whether you want to have a diagnostic test to get more information - there’s more about making these difficult decisions later on.

Diagnostic tests

A diagnostic test can tell you for certain whether your baby has Down’s syndrome or spina bifida or some other major health problem. The result is conclusive: it’s a yes/no situation.

Name of diagnostic test

When you can have the test

Chorionic villus sampling Around 11 weeks of pregnancy
Amniocentesis 13-18 weeks of pregnancy
Ultrasound scan (although this
may only be a screening test in
some cases)
Any time from 8 weeks of pregnancy

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